Retatrutide
Retatrutide is a peptide currently under advanced clinical investigation for its activity across multiple metabolic pathways. It is designed to act on three key receptors involved in glucose and energy regulation:
- GLP-1 (glucagon-like peptide-1)
- GIP (glucose-dependent insulinotropic polypeptide)
- Glucagon receptors
Through this triple-agonist mechanism, retatrutide has been studied for its effects on insulin secretion, regulation of glucose production, gastric emptying, and appetite-related signaling.